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Regulatory Research and Medicine Evaluation

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ORIGINAL ARTICLES

 
Issue Title
 
Online First Strategic Indicators in the Development of Original Medicinal Products in 2024: Analysis of Pipelines of International Pharmaceutical Leaders Abstract   PDF (Rus)
L. S. Litvin, E. A. Kulikova
 
Online First Qualitative Analysis of Valeriana officinalis leaf by Thin-Layer Chromatography Abstract   PDF (Rus)
A. Yu. Fisiuk, O. V. Mushkina, N. S. Golyak, O. A. Yorshyk
 
Online First Distribution Study of 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide and Its Metabolites in Rats Abstract   PDF (Rus)
I. I. Yaichkov, A. L. Khokhlov, M. K. Korsakov, N. N. Volkhin, S. S. Petukhov, O. E. Lazariants, A. V. Korovina
 
Online First Development and Validation of an Analytical Procedure for the Quantitative Determination of Total Flavonoids in Red-Stem Buckwheat Herb (Fagopyrum rubricaulis) by Spectrophotometry Abstract   PDF (Rus)
A. V. Mitishev, E. E. Kurdyukov, M. G. Makartseva, Y. M. Nemova, D. G. Elistratov, A. S. Paksyaev
 
Online First Readability Testing as a Tool to Assess the Understanding of Medical Terms Used in Package Leaflets Abstract   PDF (Rus)
E. I. Morkovin, E. Yu. Sorokina, A. G. Solodovnikov, D. V. Kurkin, A. A. Selezneva, S. A. Leshkova, A. V. Zaborovsky
 
Online First Excretion Study of 5-[5-(Trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide in Rats Abstract   PDF (Rus)
I. I. Yaichkov, A. L. Khokhlov, M. K. Korsakov, N. N. Volkhin, S. S. Petukhov, V. E. Zaykova, O. E. Lazariants
 
Vol 11, No 4 (2021) Determination of Vancomycin B and Vancomycin Impurities by Liquid Chromatography Abstract   PDF (Rus)
S. I. Kuleshova, E. P. Simonova, O. N. Vysochanskaya
 
Vol 11, No 3 (2021) Determination of the Critical Phases of the Experimental Research Using Laboratory Animals: Risk Analysis Abstract   PDF (Rus)
S. V. Khodko, M. N. Makarova, V. G. Makarov, S. S. Salynov, N. V. Rodionova
 
Vol 11, No 3 (2021) Determination of Folic Acid in Multivitamin Preparations by Reversed Phase HPLC Abstract   PDF (Rus)
A. S. Alekseeva, M. V. Gavrilin, T. B. Shemeryankina, M. S. Smirnova, E. P. Fedorova, T. M. Kargina, O. O. Novikov, S. A. Kovaleva, N. N. Boyko
 
Vol 11, No 2 (2021) Detection of Pyrogens in Hormonal Implants Using the LAL Test Abstract   PDF (Rus)
N. P. Neugodova, O. V. Shapovalova, G. A. Sapozhnikova, E. O. Stepanyuk
 
Vol 11, No 2 (2021) Stability of Ready-to-Use and Laboratory-Prepared Culture Media Abstract   PDF (Rus)
S. I. Kuleshova, S. A. Protsak, S. A. Lisunova, G. Yu. Romanyuk
 
Vol 11, No 2 (2021) Determination of Arbutin in Herbal Medicinal Products Abstract   PDF (Rus)
N. P. Antonova, S. S. Prokhvatilova, E. P. Shefer, A. M. Kalinin, I. M. Morgunov, T. A. Golomazova, U. S. Legon’kova
 
Vol 11, No 1 (2021) Limitations of NIR Spectrometry as an Identification Test for Active Ingredients in Medicinal Products Abstract   PDF (Rus)
N. E. Kuz'mina, S. V. Moiseev, B. K. Romanov
 
Vol 11, No 1 (2021) Use of Biomarkers in Pharmacokinetics Studies of Medicinal Products of Natural Origin Abstract   PDF (Rus)
V. M. Kosman, N. M. Faustova, M. V. Karlina, V. G. Makarov, M. N. Makarova
 
Vol 10, No 4 (2020) Validation Parameters as Applied to Methods for Quantification of Microorganisms in Medicinal Products Abstract   PDF (Rus)
I. A. Buylova, O. V Gunar
 
Vol 11, No 1 (2021) Improvement of Methods of Standardisation of Medicinal Products Made from Veratrum Lobelianum Rhizomes with Roots Abstract   PDF (Rus)
N. P. Antonova, I. M. Morgunov, S. S. Prokhvatilova, E. P. Shefer, O. V. Evdokimova, A. V. Beketova, M. N. Lyakina
 
Vol 10, No 4 (2020) Risk-Based Approach to the Assessment of Sanitary Safety of Vivariums and Breeding Facilities, and Health Status of Personnel and Laboratory Animals Abstract   PDF (Rus)
E. D. Bondareva, K. E. Borovkova, M. N. Makarova
 
Vol 11, No 1 (2021) Development of a Comprehensive HPLC Method for Determination of Product-related Impurities and Assay of Active Ingredients in Papaverine Hydrochloride Products Abstract   PDF (Rus)
N. P. Antonova, E. P. Shefer, N. E. Semenova, S. S. Prokhvatilova, A. M. Kalinin, S. A. Kuchugurin, V. N. Makukhin
 
Vol 10, No 4 (2020) Experience in Validation of Methods for Determination of Radiochemical Impurities in Radiopharmaceuticals Abstract   PDF (Rus)
A. O. Malysheva, G. E. Kodina, E. A. Lyamtseva, N. A. Taratonenkova, A. S. Lunev
 
Vol 10, No 3 (2020) Relevant Issues of Planning Bioequivalence Studies of Drugs with a Narrow Therapeutic Range Abstract   PDF (Rus)
D. P. Romodanovsky
 
Vol 10, No 3 (2020) HPLC-MS/MS Method for Quantitation of Sildenafil and Its Active Metabolite in Human Plasma Abstract   PDF (Rus)
G. G. Rodionov, I. I. Shantyr, I. E. Ushal, E. V. Svetkina, E. A. Kolobova, K. A. Zakharov
 
Vol 10, No 2 (2020) Effect of Sample Preparation and Chromatographic Conditions on Background Signal Abstract   PDF (Rus)
V. M. Kosman, M. V. Karlina, O. N. Pozharitskaya
 
Vol 10, No 2 (2020) Determination of Anthracene Derivatives in the Antihaemorrhoidal Medicinal Herb Mixture Proctophytol® Using the European Pharmacopoeia Method Abstract   PDF (Rus)
N. P. Antonova, I. M. Morgunov, S. P. Prokhvatilova, E. P. Shefer, A. M. Kalinin, T. A. Golomazova
 
Vol 10, No 1 (2020) Expert Approaches to the Assessment of Losartan Drugs Bioequivalence Abstract   PDF (Rus)
D. P. Romodanovsky, D. V. Goryachev
 
Vol 10, No 1 (2020) Comparative Analysis of Heavy Metal and Arsenic Content in Various Herbal Dosage Forms Marketed in Russia Abstract   PDF (Rus)
V. M. Shchukin, N. E. Kuz’mina, Yu. N. Shvetsova, A. I. Luttseva
 
Vol 9, No 4 (2019) Current Approaches to Valerian Tincture Standardisation in Terms of Assay Abstract   PDF (Rus)
N. P. Antonova, E. P. Shefer, A. M. Kalinin, N. E. Semenova, S. S. Prokhvatilova, I. M. Morgunov
 
Vol 9, No 4 (2019) The Mechanism of Action of Follistatin-like Protein-1 (FSTL-1) Abstract   PDF (Rus)
V. G. Kukes, Yu. V. Olefir, B. K. Romanov, A. B. Prokofiev, E. V. Parfenova, M. A. Boldyreva, O. A. Goroshko, O. K. Parfenova, A. A. Gazdanova, E. Yu. Demchenkova
 
Vol 9, No 4 (2019) X-ray Diffraction Analysis of Linezolid Crystalline Forms as Part of Quality Control Abstract   PDF (Rus)
V. S. Kuzmin, V. V. Chernyshev, A. I. Luttseva
 
Vol 9, No 3 (2019) Evaluation of Bioequivalence of Generic Imatinib Products and Generic Tacrolimus Products Based on Indirect Comparison of the Results of Their Bioequivalence Studies Abstract   PDF (Rus)
D. V. Goryachev, N. E. Uvarova
 
Vol 9, No 3 (2019) Optimisation of the Procedure of Cefepime Extraction from Biological Material Abstract   PDF (Rus)
A. A. Bezyazychnaya, V. K. Shormanov, L. E. Siplivaya
 
Vol 9, No 3 (2019) Application of HPLC for Evaluation and Standardisation of Hawthorn Flower Herbal Substance Abstract   PDF (Rus)
N. P. Antonova, E. P. Shefer, N. E. Semenova, A. M. Kalinin, S. S. Prokhvatilova, I. M. Morgunov
 
Vol 9, No 3 (2019) Assessment of the Effectiveness of Implementation of Information Systems for Medicines Evaluation Abstract   PDF (Rus)
K. A. Koshechkin, Yu. V. Olefir
 
Vol 9, No 2 (2019) Validation of Enzyme Immunoassay for Preclinical Pharmacokinetic Trials of Rituximab Abstract   PDF (Rus)
V. V Pisarev, Maria M Ulyashova, Gelia N Gildeeva
 
Vol 9, No 2 (2019) Applicability of Capillary Gas-Liquid Chromatography for Determination of Parabens in Pharmaceutical Analysis Abstract   PDF (Rus)
A. N. Ioutsi, M. A. Sumtsov, D. A. Artyushenko, D. V. Bychenkov, A. N. Blinov
 
Vol 9, No 1 (2019) Development of identification test methods for triptorelin acetate and goserelin acetate substances using NMR spectroscopy Abstract   PDF (Rus)
S. V Moiseev, N. E. Kuz’mina, A. I. Luttseva
 
Vol 8, No 4 (2018) Improvement of Tests for the Control of Impurities in Antimicrobial Medicinal Products by Chromatographic Methods: Ciprofloxacin Case Study Abstract   PDF (Rus)
S. I. Kuleshova, V. S. Udalov, E. P. Simonova, I. A. Denisova, D. V. Mishkin
 
Vol 8, No 4 (2018) Comparative Evaluation of Assay Methods Used to Determine Anthracene Derivatives in Herbal Substances and Herbal Medicinal Products Abstract   PDF (Rus)
N. P. Antonova, I. M. Morgunov, S. S. Prokhvatilova, E. P. Shefer, A. M. Kalinin
 
Vol 8, No 3 (2018) EVALUATION OF THE EFFICACY OF DEPRESSIVE DISORDERS PHARMACOTHERAPY USING QUANTITATIVE PHARMACO-EEG Abstract   PDF (Rus)   PDF (Eng)
O. M. Kudelina, Yu. S. Maklyakov, D. P. Khloponin, V. G. Zaika, E. V. Gantsgorn, A. V. Safronenko
 
Vol 8, No 3 (2018) ELIMINATION OF FALSE RESULTS OF MEDICINES MICROBIOLOGICAL TESTING Abstract   PDF (Rus)
I. A. Buylova, N. G. Sakhno, G. M. Bulgakova, O. V. Gunar
 
Vol 8, No 3 (2018) A METHODOLOGICAL APPROACH TO DESIGNING EXPERIMENTS WHEN DEALING WITH IDENTIFICATION TESTS FOR MEDICINAL PRODUCT COMPONENTS (AS ILLUSTRATED BY ASCORBIC ACID) Abstract   PDF (Rus)   PDF (Eng)
Yu. B. Purim, M. L. Kruglyakova, L. N. Bulanova, M. V. Agapkina, L. N. Stronova, T. N. Bokovikova, E. P. Gernikova
 
Vol 8, No 2 (2018) EXPERIMENTAL TESTING OF THE MODIFIED METHOD OF INTRAVITREAL INJECTION IN THE RABBIT EYE Abstract   PDF (Rus)
A. V. Kalatanova, A. E. Katelnikova, M. N. Makarova, V. G. Makarov
 
Vol 8, No 2 (2018) EXPERIMENTAL TESTING OF AN IN VIVO METHOD OF PHOTOTOXICITY EVALUATION Abstract   PDF (Rus)
V. А. Vavilova, E. V. Shekunova, V. A. Kashkin, M. N. Makarova, V. G. Makarov, A. Ya. Khaymenov
 
Vol 8, No 2 (2018) ASPECTS OF MEDICINES QUALITY EVALUATION BY ELECTRICAL SENSING ZONE METHOD Abstract   PDF (Rus)
E. S. Novik, A. V. Dorenskaya, N. A. Borisova, O. V. Gunar
 
Vol 8, No 2 (2018) PROBLEMS OF IODIDE IONS DETERMINATION IN MULTIVITAMINS BY INDUCTIVELY COUPLED PLASMA ATOMIC-EMISSION SPECTROMETRY Abstract   PDF (Rus)
V. M. Shchukin, E. Yu. Severinova, N. E. Kuz’mina, V. A. Yashkir, V. A. Merkulov
 
Vol 8, No 1 (2018) REGULATORY AND METHODOLOGICAL ASPECTS OF STUDYING ALLERGENIC PROPERTIES OF NEW MEDICINES AT THE PRECLINICAL STAGE Abstract   PDF (Rus)
K. L. Kryshen, A. E. Katelnikova, A. A. Muzhikyan, M. N. Маkarova, V. G. Makarov
 
Vol 8, No 1 (2018) THE USE OF A CHROMATOGRAPHIC COLUMN PACKED WITH AMIDE SORBENT FOR THE ANALYSIS OF PARABENS Abstract   PDF (Rus)
A. S. Osipov, O. A. Popova, S. E. Milkina, T. N. Gretskaya, A. I. Sulimenkova
 
Vol 8, No 1 (2018) COMPARATIVE ANALYSIS OF REQUIREMENTS FOR QUALITY CONTROL OF ETHINYL ESTRADIOL AND LEVONORGESTREL CONTAINING MEDICINAL PRODUCTS Abstract   PDF (Rus)
V. I. Seredenko, A. V. Korolev, L. G. Maslov, T. Yu. Belova, N. N. Dolgushina
 
Vol 7, No 3 (2017) Molecular screening for potential selective antagonists of TRPA1 ion channel Abstract   PDF (Rus)
E. A. Beskhmelnitsyna, D. V. Kravchenko, M. V. Pokrovsky, M. V. Korokin, A. A. Peresypkina, E. I. Varavin, D. A. Kostina
 
Vol 7, No 3 (2017) Results of an opinion poll devoted to unification of instructions for interchangeable medicines Abstract   PDF (Rus)
N. G. Goloenko, R. I. Yagudina, B. K. Romanov, D. G. Karapetyan, A. Yu. Kulikov, M. V. Protsenko, G. T. Abdrashitova
 
Vol 7, No 4 (2017) Plan of action for carbapenem antibiotics sterility testing Abstract   PDF (Rus)
S. I. Kuleshova, S. A. Protsak, S. A. Lisunova, G. Yu. Romanyuk, E. N. Semenova
 
Vol 7, No 4 (2017) Development of the method of trifluoroacetates determination in glatiramer acetate pharmaceutical substance by19F NMR spectroscopy Abstract   PDF (Rus)
S. V. Moiseev, V. I. Krylov, N. E. Kuz’Mina, V. A. Yashkir, V. A. Merkulov
 
Vol 7, No 3 (2017) Substantiation of conditions for determination of related substances in bisoprolol fumarate by HPLC Abstract   PDF (Rus)
O. A. Baturina, E. V. Chaykovskaya, E. P. Gernikova, T. N. Bokovikova, L. A. Stronova, Yu. R. Biglova, S. A. Manaeva, E. S. Tolmacheva
 
Vol 7, No 3 (2017) Recommendations for selection of a liquid stationary phase and geometric parameters of the column when determining triethylamine by gas chromatography Abstract   PDF (Rus)
A. N. Ioutsi, M. A. Sumtsov, A. T. Sarnitskaya, A. N. Blinov
 
Vol 7, No 3 (2017) Validation of the procedure for determination of amino acids composition of glatiramer acetate by C-13 NMR spectroscopy Abstract   PDF (Rus)
N. E. Kuz’Mina, S. V. Moiseev, V. I. Krylov, A. A. Kutin, E. A. Zhukov, V. A. Yashkir, V. A. Merkulov
 
Vol 7, No 3 (2017) An alternative method of loss on drying determination in herbal medicinal products Abstract   PDF (Rus)
N. P. Antonova, I. M. Morgunov, S. S. Prohvatilova, E. P. Shefer, A. M. Kalinin
 
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