RETRACTED: Efficacy and safety of medicines: the value and opportunities of clinical pharmacology
Abstract
Brief description of the opportunities and benefits of applying the methodology of clinical pharmacology and personalized medicine, pharmacokinetics, and pharmacodynamics of medicines, as well as the possibilities of evaluation of metabolic biotransformation and drug interactions to improve the efficacy, safety, therapeutic and pharmacodynamic effects of medicines, is given. These features and techniques should be extensively used for expert evaluation of efficacy and safety of drugs. The introduction of modern methods of diagnostics and treatment in clinical practice will require building a system that could be implemented in the Centres of personalized medicine.
About the Authors
M. V. Zhuravleva
Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
V. G. Kukes
Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
A. B. Prokofiev
Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
V. V. Arkhipov
Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Yu. V. Olefir
Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
S. Yu. Serebrova
Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
A. V. Sokolov
Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
D. A. Sychev
Russian Medical Academy of Postgraduate Education of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
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Review
For citations:
Zhuravleva M.V., Kukes V.G., Prokofiev A.B., Arkhipov V.V., Olefir Yu.V., Serebrova S.Yu., Sokolov A.V., Sychev D.A. RETRACTED: Efficacy and safety of medicines: the value and opportunities of clinical pharmacology. The Bulletin of the Scientific Centre for Expert Evaluation of Medicinal Products. 2015;(2):20-24. (In Russ.)
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