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Retrospective analysis of gender differences in the progression and treatment of acute myocardial infarction in the Republic of Komi

Abstract

The article summarises the results of a retrospective study of established acute myocardial infarction in men and women who were hospitalized between 2003 and 2011. Medical records of 1403 patients, 43.98 % of which were women, were analyzed. The analysis showed that myocardial infarction occurred on average 10 years later in women than in men. The women were more likely to have comorbidities including diabetes, obesity, hypertension, dyslipidemia. The analysis revealed an increase in the frequency of reperfusion therapy and coronary angiography. Laboratory test results showed that female patients had higher levels of blood glucose, cholesterol, and arterial pressure and lower hemoglobin levels and glomerular filtration rates than men. The analysis showed a five-fold increase in the frequency of prescribing statins in men and a seven-fold increase in women.

About the Authors

O. N. Kurochkina
Pitirim Sorokin Syktyvkar State University
Russian Federation


M. A. Sinayskaya
Central Polyclinic of Syktyvkar
Russian Federation


References

1. Zemlyanova EV, Semenova VG. Analysis of the dynamics of mortality in Russia and Europe. Moscow; 2007 (in Russian).

2. Bunova SS, Usacheva EV, Zamahina OV. The dynamics of myocardial infarction incidence in the regions of the Russian Federation for the 11-year period (2002– 2012). Sotsialnye aspecty zdoroviya naseleniya 2014; (6). Available from: http://vestnik.mednet.ru/content/view/624/27/lang,ru (in Russian).

3. Cardiovascular Disease: Women’s ¹ 1 Health Threat. Available from: https://goo.gl/cwHuqB.

4. Tsygankova OV, Platonova DYu, Bondareva ZG, Starichkov AA, Latyntseva LD. Coronary disease in women: pathogenetic and pathological features of formation and clinical course. Problemy zhenskogo zdoroviya 2013; (4): 50–6 (in Russian).

5. Boldueva SA, Trostyanetskaya NA, Leonova IA. Gender features of acute myocardial infarction:. The results of a retrospective study. Problemy zhenskogo zdoroviya 2012; (2): 11–6 (in Russian).

6. Atroschenko ES, Atroschenko IE. Coronary heart disease in women: a clinical and epidemiological features. Problemy zhenskogo zdoroviya 2012; (3): 62–9 (in Russian).

7. Mandelzweig L, Battler A, Boyko V, Bueno H, Danchin N, Filippatos G, et al. Euro Heart Survey Investigators. The second Euro Heart Survey on acute coronary syndromes: Characteristics, treatment, and outcome of patients with ACS in Europe and the Mediterranean Basin in 2004. Eur Heart J. 2006; 27(19): 2285–93.

8. Kurochkina ON, Spassky AA, Khokhlov AL. The course of myocardial infarction from the position of gender differences: results of a retrospective study. Problemy zhenskogo zdoroviya 2012; (3): 18–23 (in Russian).

9. Semakina AV, Saygitov RT, Glezer MG. Clinical and medical history, and laboratory and instrumental characteristics of myocardial infarction and early post-hospital prognosis of the disease in men and women. Problemy zhenskogo zdoroviya 2010; (2): 12–21 (in Russian).

10. Povorotov VM, Shevchenko AI, Islamov RR. Dynamic management of patients with acute coronary syndrome in primary non-invasive vascular center (according to the registers RECORD and RECORD-2). Ratsionalnaya farmakoterapiya v kardiologii 2011; 7(5): 596–600 (in Russian).

11. Ehrlich AD, Matskeplishvili ST, Gratsiansky NA, Buziashvili YuI. First Moscowregister of acute coronary syndrome: characteristics of patients, treatment and outcomes for the hospital stay. Kardiologiya 2013; 53(12): 4–13 (in Russian).

12. Oshchepkova EV, Boytsov SA, Dovgalevsky PYu. Comparative analysis of the data of the Russian and foreign registers of acute coronary syndrome. Kardiologicheskiy vestnik 2010; (1): 82–6 (in Russian).

13. Stramba-Badiale M. Women and research on cardiovascular diseases in Europe: a report from the European Heart Health Strategy (EuroHeart) project. Eur Heart J. 2010; 31(14): 1677–81.

14. Kuimov AD. Myocardial infarction in women. Novosibirsk: Nauka; 2006 (in Russian).

15. Tavlueva EV. Gender features of formation and prognosis of myocardial infarction with ST-segment elevation. Dr. Med. Sci [thesis]. Kemerovo; 2012 (in Russian).

16. Oshchepkova EV, Boytsov SA, Dovgalevsky PYu. Comparative analysis of the data of the Russian and foreign registers of acute coronary syndrome. Kardiologicheskiy vestnik 2010; (1): 82–6 (in Russian).

17. Ehrlich AD, Gratsiansky NA. RECORD register. Treatment of patients with acute coronary syndromes in hospitals with and without the possibility of the invasive coronary procedures. Kardiologiya 2010; 50(7): 8–14 (in Russian).

18. Martsevich SYu, Ginzburg ML, Kutishenko NP, Zagrebelnyi AV, Balashov IS, Garkina LG. Dynamics of pre-hospital care of patients with acute coronary syndrome from 2005 to 2014 according to LIS register. Ratsionalnaya farmakoterapiya v kardiologii 2014; 10(6): 631–3 (in Russian).

19. McCormick D, Gurwitz JH, Lessard D, Yarzebski J, Gore JM, Goldberg RG. Use of aspirin, b-Blockers, and Lipid-Lowering Medications Before Recurrent Acute Myocardial Infarction. Missed Opportunities for Prevention? Arch Intern Med. 1999; 159: 561–7.

20. Martsevich SYu, Ginzburg ML, Kutishenko NP. Lyubertsy mortality study (LIS study): factors affecting the life of remote prognosis after myocardial infarction. Profilakticheskaya meditsina 2013; (2): 32–8 (in Russian).

21. Yeh RW, Sidney S, ChandraM. Population Trends in the Incidence and Outcomes of Acute Myocardial Infarction. N Engl J Med. 2010; 362: 2155–65.


Review

For citations:


Kurochkina O.N., Sinayskaya M.A. Retrospective analysis of gender differences in the progression and treatment of acute myocardial infarction in the Republic of Komi. The Bulletin of the Scientific Centre for Expert Evaluation of Medicinal Products. 2017;7(1):41-46. (In Russ.)

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ISSN 3034-3062 (Print)
ISSN 3034-3453 (Online)