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An alternative method of loss on drying determination in herbal medicinal products

Abstract

The article compares two methods of loss on drying determination in herbal medicinal products: drying using an infrared thermographic moisture analyzer and drying carried out in a drying cabinet. Data obtained with the moisture analyzer were shown to be sufficient for determination of loss on drying in herbal medicinal products of different morphological groups and were generally consistent with the data obtained by the traditional pharmacopoeial method - drying in a drying cabinet. The article demonstrates the feasibility of performing loss on drying test using an infrared thermographic moisture analyzer.

About the Authors

N. P. Antonova
Scientific Centre for Expert Evaluation of Medicinal Products
Russian Federation


I. M. Morgunov
Scientific Centre for Expert Evaluation of Medicinal Products
Russian Federation


S. S. Prohvatilova
Scientific Centre for Expert Evaluation of Medicinal Products
Russian Federation


E. P. Shefer
Scientific Centre for Expert Evaluation of Medicinal Products
Russian Federation


A. M. Kalinin
Scientific Centre for Expert Evaluation of Medicinal Products
Russian Federation


References

1. The State Pharmacopoeia of the Russian Federation. 13th ed. V. 1–3. Moscow; 2015 [Internet]. Available from: http://femb.ru/feml (in Russian).

2. European Pharmacopoeia. 9th ed. Strasbourg; 2017 [Internet]. Available from: http://online.edqm.eu/EN/entry.htm.

3. Antonova NP, Prokhvatilova SS, Shefer EP, Kalinin AM. Specifics of herbal drugs quality testing with the examples of typical criticism of laboratory testing of those. The Bulletin of the Scientific Centre for Expert Evaluation of Medicinal Products 2015; (3): 18–22 (in Russian).

4. Kiptelaya LV, Zagorulko AN. IR-drying of fruit and berry raw materials. Scientific Journal of NRU ITMO 2014; (3): 80–86 (in Russian).

5. Akulich AV, Temruk AV. Drying of fruit and vegetable raw materials using infrared radiation. Food Industry 2009; (9): 12–13 (in Russian).

6. Zavaliy AA, Snezhkin YuF. Development and thermal modeling of devices for infrared drying of thermolabile materials. Simferopol: ARIAL; 2016 (in Russian).


Review

For citations:


Antonova N.P., Morgunov I.M., Prohvatilova S.S., Shefer E.P., Kalinin A.M. An alternative method of loss on drying determination in herbal medicinal products. The Bulletin of the Scientific Centre for Expert Evaluation of Medicinal Products. 2017;7(3):182-185. (In Russ.)

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ISSN 3034-3062 (Print)
ISSN 3034-3453 (Online)