The use of NMR-spectroscopy in pharmacopoeial analysis
Abstract
The article illustrates the prospects of using nuclear magnetic resonance spectroscopy for complex, fast and reliable determination of key quality attributes of drug substances while performing pharmacopoeial analysis.
Keywords
ЯМР-спектроскопия,
фармакопейный анализ,
структурная интерпретация ЯМР-спектров,
подлинность лекарственных субстанций,
количественное определение,
молекулярно-массовое распределение,
молярное замещение,
NMR-spectroscopy,
pharmacopoeial analysis,
structural interpretation of NMR spectra,
identification of drug substances,
assay,
molar mass distribution,
molar substitution
About the Authors
S. V. Moiseev
Scientific Centre for Expert Evaluation of Medicinal Products
Russian Federation
Russian Federation
V. I. Krylov
Scientific Centre for Expert Evaluation of Medicinal Products
Russian Federation
Russian Federation
N. E. Kuzmina
Scientific Centre for Expert Evaluation of Medicinal Products
Russian Federation
Russian Federation
V. A. Yashkir
Scientific Centre for Expert Evaluation of Medicinal Products
Russian Federation
Russian Federation
V. A. Merkulov
Scientific Centre for Expert Evaluation of Medicinal Products
Russian Federation
Russian Federation
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Review
For citations:
Moiseev S.V., Krylov V.I., Kuzmina N.E., Yashkir V.A., Merkulov V.A. The use of NMR-spectroscopy in pharmacopoeial analysis. The Bulletin of the Scientific Centre for Expert Evaluation of Medicinal Products. 2016;(2):53-57. (In Russ.)
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