Optical methods in the study of drug chiral proporties. I. Valine in aqueous solutions with different deuterium content
Abstract
Two optical methods - polarimetry and laser light diffraction - have been used to study valine aqueous solutions. It has been shown that optical activity of valine enantiomers depends on deuterium content in aqueous solutions. The influence of deuterium-dependant heterophase clusters of water on optical activity of valine aqueous solutions has been discussed.
About the Authors
A. V. Syroeshkin
Peoples’ Friendship University of Russia, Medical Institute
Russian Federation
Russian Federation
T. V. Pleteneva
Peoples’ Friendship University of Russia, Medical Institute
Russian Federation
Russian Federation
E. V. Uspenskaya
Peoples’ Friendship University of Russia, Medical Institute
Russian Federation
Russian Federation
O. V. Levitskaya
Peoples’ Friendship University of Russia, Medical Institute
Russian Federation
Russian Federation
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Review
For citations:
Syroeshkin A.V., Pleteneva T.V., Uspenskaya E.V., Levitskaya O.V. Optical methods in the study of drug chiral proporties. I. Valine in aqueous solutions with different deuterium content. The Bulletin of the Scientific Centre for Expert Evaluation of Medicinal Products. 2016;(1):25-28. (In Russ.)
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