Shared knowledge centre (research and education centre) of the Peoples’ Friendship University of Russia as a modern experimental basis for the development of drug standards

Shared Knowledge Centre (Research and Education Centre) of the Peoples’ Friendship University of Russia (SKC (REC) PFUR) was established in 2009. It is equipped with modern advanced measuring and testing equipment. On the basis of SKC (REC) various scientific and research projects are conducted, such as the development and formulation of medicines; quality control and standardization of medicines and substances, etc. The research results became a basis for a number of general monographs and monographs to be included in the Russian State Pharmacopoeia XIII edition, in particular, «Mass Spectrometry», «Fatty oils» etc. At the moment the employees of SKC (REC) are developing technologies and methods of standardization for dosage forms such as transdermal patch, buccal films, floating tablet and other innovative dosage forms, which will be used for further development of the general monographs and monographs for the future Russian State Pharmacopoeia editions.

Государственная фармакопея XIII изд, общая фармакопейная статья, фармакопейная статья, масс-спектрометрия, жирные масла, полиморфизм, кристалличность, суппозитории, Russian State Pharmacopoeia XIII edition, general pharmacopoeia monograph, pharmacopeia monograph, mass spectrometry, fatty oils, polymorphism, crystallinity, suppositories

1. Abramovich RA. The basics of design and technology of suppositories with domestic substances. Dr. Pharm. Sci [dissertation]. Moscow; 2013 (in Russian).

2. Goryainov SV, Homik AS, Kalabin GA, Vandyshev VV, Abramovich RA. Fatty acid composition of seeds of Punica granatum L. waste from receiving pomegranate juice. Vestnik RUDN 2012; (1): 10–15 (in Russian).

3. Goryainov SV, Labziui Z, Suslina SN, Vandyshev VV, Kalabin GA. Comparative study samples seed oil Argania spinosa, obtained by different methods, methods 1H NMR spectroscopy and mass spectrometry. Voprosy biologicheskoy, meditsinskoy i farmatsevticheskoy himii 2013; (4): 10–15 (in Russian).

4. Potanina OG. Improved standardization and quality control of medicinal plant materials and dosage forms thereof on the basis of the microscopic method of investigation. Dr. Pharm. Sci [dissertation]. Moscow; 2003 (in Russian).

5. Potanina OG, Samylina IA. Pharmacopoeial requirements for microscopic analysis of medicinal plants. Farmatsiya 2015; (4): 47–48 (in Russian).

6. Potanina OG, Samylina IA. Improving the requirements for the development of common methods of analysis pharmacopoeia of medicinal plants. Farmatsiya 2011; (3): 46–47 (in Russian).

7. Chistyakov VV. Quality problems of substances in the production of generics. Medicines: applied pharmacology and personalized pharmacotherapy; 2010 (in Russian).

8. Chistyakov VV. The relationship of the crystal structure of substance, pharmacokinetics and drug efficacy. In: Kukes VG, ed. Clinical pharmacokinetics: theoretical, applied and analytical aspects: guidance. Moscow: GEOTAR Media; 2009. P. 432 (in Russian).

9. Chernetsova ES, Khomyakov YuYu, Goryainov SV, Ovcharov MV, Abramovich RA, Bochkov PO, Zatonsky GV, Zhokhov SS. A comparison of the capabilities of Direct Analysis in Real Time mass spectrometry and gas chromatography — mass spectrometry for the analysis of mint essential oil samples. Mendeleev Communications 2010; 20(5): 299–300.

10. Borisov RS, Polovkov NY, Gorjainov SV, Zaikin VG. Determination of composition of poly(ethylene-copropylene) glycols at molecular level by MALDI mass spectrometry following preliminary derivatization. International Journal of Polymer Analysis and Characterization 2012; 17: 608–615.