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Radioisotope Products and the Medicine of the Future: an IAEA Perspective

https://doi.org/10.30895/1991-2919-2022-423

Abstract

The production and application of radioisotopes and radiopharmaceuticals is a major peaceful application of nuclear science and technology and has opened new gateways for nuclear medicine in critical human diseases. Advances in the production of radioisotopes via nuclear reactors, accelerators, fission, etc. has facilitated the access to these products for Member States. 99Mo, 131I, 177Lu are among the most essential radioisotopes for nuclear medicine and human health and their production and availability always has been an important theme for professional societies and the International Atomic Energy Agency (IAEA). In the meantime, a large list of theranostic radioisotopes including but not limited to 89Zr, 68Ga, 225Ac, Cu-series, Sc-series, Tb-series etc. has provided a powerful toolbox for clinicians and the IAEA is taking steps to ensure their safe and appropriate application in radiopharmacy. The Agency promotes the production and application routes, including research reactors, cyclotrons, linear accelerators, and other cutting-edge methods, according to international and national guidelines and regulations. The IAEA also conducts activities such as Coordinated Research Projects (CRPs), Technical Meetings (TMs), national/regional training courses and conferences, to support and join forces with international professional societies in the development of human resources and research and development activities. Development of databases and freely available publications for all Member States are other useful means to support Member States in radiopharmaceutical sciences.

About the Authors

A. Jalilian
Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna International Centre
Austria

Amirreza Jalilian, Ph. D. 

Vienna



A. Korde
Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna International Centre
Austria

Aruna Korde, Ph. D. 

Vienna



V. Starovoitova
Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna International Centre
Austria

Valeriia Starovoitova, Ph. D. 

Vienna



J. Jr. Osso
Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna International Centre
Austria

Joao Osso Jr., Ph. D. 

Vienna



A. Koning
Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna International Centre
Austria

Arjan Koning, Ph. D. 

Vienna



N. Pessoa Barradas
Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna International Centre
Austria

Nuno Pessoa Barradas, Ph. D. 

Vienna



C. Horak
Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna International Centre
Austria

Celina Horak, Ph. D. 

Vienna



M. Denecke
Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna International Centre
Austria

Melissa Denecke, Ph. D. 

Vienna



References

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For citations:


Jalilian A., Korde A., Starovoitova V., Osso J.J., Koning A., Pessoa Barradas N., Horak C., Denecke M. Radioisotope Products and the Medicine of the Future: an IAEA Perspective. Bulletin of the Scientific Centre for Expert Evaluation of Medicinal Products. Regulatory Research and Medicine Evaluation. 2022;12(4):364-378. https://doi.org/10.30895/1991-2919-2022-423

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ISSN 3034-3062 (Print)
ISSN 3034-3453 (Online)