Standardization of the peptide preparation timocin
Abstract
It is currently established that some low molecular weight peptides possess immunomodulating activity and are used as peptide preparations. One of the most important trace elements playing an important role in the functioning of the immune system is zinc. The performed research became the basis for the development of the immunomodulatory preparation timocin, in a form of aqueous solution of zinc coordination compounds with dipeptide isoleucyl-tryptophan, which has been registered in the Republic of Tajikistan as an immunomodulating preparation. The research allowed to perform standardization and develop pharmacopoeia monograph for the reference standard and the finished dosage form of the immunomodulatory preparation timocin.
About the Authors
G. M. Bobizoda
Education Academy of the Tajikistan Republic
Russian Federation
Russian Federation
N. D. Bunyatyan
I. M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
A. N. Shakhmatov
«Zand Ltd» (Dushanbe)
Russian Federation
Russian Federation
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Review
For citations:
Bobizoda G.M., Bunyatyan N.D., Shakhmatov A.N. Standardization of the peptide preparation timocin. The Bulletin of the Scientific Centre for Expert Evaluation of Medicinal Products. 2016;(1):45-49. (In Russ.)
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